Is this answer correct? I can’t judge, as I have no idea how aspirin active compound is synthetized.
Answer from gtp-4:
Aspirin, also known as acetylsalicylic acid (ASA), can be synthesized through a chemical reaction involving salicylic acid and acetic anhydride. Here’s the general process:
Salicylic Acid Preparation (if needed): If starting from other compounds like phenol, salicylic acid may need to be synthesized first.
Acetylation of Salicylic Acid: Salicylic acid is reacted with acetic anhydride.
[
\text{{salicylic acid}} + \text{{acetic anhydride}} \rightarrow \text{{acetylsalicylic acid}} + \text{{acetic acid}}
]
Purification: The crude product is often purified by recrystallization, typically using a solvent like ethanol or water.
Drying: The purified aspirin is dried to remove any remaining solvent.
Characterization: The synthesized aspirin may be characterized using methods like melting point determination, infrared spectroscopy, or other analytical techniques to ensure purity and identity.
In a laboratory setting, the reaction is often catalyzed by an acid such as sulfuric acid, which speeds up the process. The reaction is typically carried out at a moderate temperature, such as around 80°C.
Safety precautions must be taken as the chemicals involved can be corrosive, and proper waste disposal is necessary.
It is known that domain knowledge is superficial for general models. One either needs a specifically trained model (such as med-palm2), or use some strategies to add memories, such as embedding databases
Is this answer correct? I can’t judge, as I have no idea how aspirin active compound is synthetized.
Answer from gtp-4:
it’s essentially correct, but also it sounds like it was lifted entirely from students lab manual (either chemistry or pharmacy)
It is known that domain knowledge is superficial for general models. One either needs a specifically trained model (such as med-palm2), or use some strategies to add memories, such as embedding databases