A graduate of the University of Melbourne, Dr Sikaris trained at the Royal Melbourne, Queen Victoria, and Prince Henry’s Heidelberg Repatriation Hospitals. He obtained fellowships from the Royal College of Pathologists of Australasia and the Australasian Association of Clinical Biochemists in 1992 and 1997 respectively.
Dr Sikaris was Director of Chemical Pathology at St Vincent’s Hospital in Melbourne between 1993 and 1996. A NATA-accredited laboratory assessor, Dr Sikaris specialises in Prostate Specific Antigen, cholesterol and quality assurance and is currently chair of the International Federation of Clinical Chemistry Committee on Analytical Quality. His expertise is highly sought and he has presented extensively at national and international symposiums.
Notes
Papers Referenced
Low density lipoprotein particle size in hypopituitary adults receiving conventional hormone replacement therapy
The Clinical Biochemistry of Obesity
The Clinical Biochemistry of Obesity—More Than Skin Deep
Association of low carbohydrate diet score with the risk of type 2 diabetes in an Australian population: A longitudinal study
The nutritional geometry of liver disease including non-alcoholic fatty liver disease
Effects of low-carbohydrate diets v. low-fat diets on body weight and cardiovascular risk factors: a meta-analysis of randomised controlled trials
Association of dietary nutrients with blood lipids and blood pressure in 18 countries: a cross-sectional analysis from the PURE study
Fructose consumption and consequences for glycation, plasma triacylglycerol, and body weight: meta-analyses and meta-regression models of intervention studies
Triglyceride is strongly associated with nonalcoholic fatty liver disease among markers of hyperlipidemia and diabetes
Severe NAFLD with hepatic necroinflammatory changes in mice fed trans fats and a high-fructose corn syrup equivalent
Soft Drink Consumption Linked with Fatty Liver in the Absence of Traditional Risk Factors
A New Targeted Lipidomics Approach Reveals Lipid Droplets in Liver, Muscle and Heart as a Repository for Diacylglycerol and Ceramide Species in Non-Alcoholic Fatty Liver
Association between non-alcoholic fatty pancreatic disease (nafpd) and the metabolic syndrome: case–control retrospective study
The mystery of evacetrapib - why are CETP inhibitors failing?
Cholesteryl ester transfer protein inhibitors: from high-density lipoprotein cholesterol to low-density lipoprotein cholesterol lowering agents?
Modification of lipoprotein metabolism and function driving atherogenesis in diabetes
Small Dense Low-Density Lipoprotein-Cholesterol Concentrations Predict Risk for Coronary Heart Disease: The Atherosclerosis Risk in Communities (ARIC) Study
Atherogenic lipoprotein phenotype. A proposed genetic marker for coronary heart disease risk.
LDL cholesterol: controversies and future therapeutic directions
Lipid measures for prediction of incident cardiovascular disease in diabetic and non-diabetic adults: results of the 8.6 years follow-up of a population based cohort study.
Carbohydrate Restriction-Induced Elevations in LDL-Cholesterol and Atherosclerosis: The KETO Trial
Short-term hyper-caloric high-fat feeding on a ketogenic diet can lower low-density lipoprotein cholesterol: the cholesterol drop experiment
Oreo Cookie Treatment Lowers LDL Cholesterol More Than High-Intensity Statin therapy in a Lean Mass Hyper-Responder on a Ketogenic Diet: A Curious Crossover Experiment
The Lipid Energy Model: Reimagining Lipoprotein Function in the Context of Carbohydrate-Restricted Diets
Notes:
Once damaged (oxidate/glycated) LDL is absorbed by macrophages and not the liver.
lipid energy hypothesis is about energy, not atherogenesis